Table 1.
Study characteristics in adult and pediatric patients.
| Patients Group | First Author (Year) | Search Period | Type of Anesthesia | Route of Magnesium Administration | Number of Included RCT | Number of Participant (Magnesium/Control) | Type of Surgery |
|---|---|---|---|---|---|---|---|
| Adult patients | Shi (2021) | October, 2020 | GA RA | IA | 11 | 677 (343/334) | Arthroscopic knee surgery |
| Ma (2021) | February, 2020 | GA RA | IV, IT, ED, local | 8 | 880 (440/440) | Cesarean section | |
| Wang (2020) | March, 2020 | RA | IT | 10 | 720 (360/360) | Surgery procedure | |
| Li (2020) | October, 2019 | RA GA + RA | ED | 11 | 724 (362/362) | Surgical procedure | |
| Ng (2020) | January, 2019 | GA RA | IV | 51 | 3311 | Non-cardiac surgery | |
| Chen (2018) | June, 2018 | GA | IV | 4 | 263 (131/132) | Laparoscopic cholecystectomy | |
| Wang (2017) | November, 2016 | RA | IT, ED | 9 | 827 | Cesarean section | |
| Zeng (2016) | January, 2016 | GA | IA | 8 | 513 (242/271) | Arthroscopic surgery | |
| Guo (2015) | September, 2014 | GA RA | IV | 27 | 1504 | Surgical procedure | |
| De Oliveira (2013) | June, 2012 | GA | IV | 20 | 1257 (639/618) | Surgical procedure | |
| Albrecht (2013) | January, 2012 | GA RA | IV | 25 | 1461 (731/730) | Surgical procedure | |
| Pascual-Ramirez (2013) | December, 2011 | RA | IT | 12 | 817 (412/405) | Below-umbilicus procedure | |
| Murphy (2013) | July, 2011 | GA RA | IV | 22 | 1177 (599/578) | Surgery procedure | |
| Pediatric patients | Kawakami (2018) | November, 2017 | RA | ED | 6 | 371 (179/192) | Surgical procedure |
| Xie (2017) | June, 2016 | GA | IV, local | 10 | 665 (333/332) | Tonsillectomy | |
| Cho (2017) | January, 2017 | GA | IV, local | 10 | 655 (328/327) | Tonsillectomy |
RCT, randomized controlled trial; GA, general anesthesia; RA, regional anesthesia; IA, intra-articular; IV, intravenous; IT, intrathecal; ED, epidural.