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. 2021 Nov 29;14(12):1241. doi: 10.3390/ph14121241

Table 1.

Evolution of the different CUSP9 regimes.

CUSP9 CUSP9* CUSP9v3 CUSP9v3r/q 1
aprepitant
-antiemetic
aprepitant aprepitant
80 mg; 1×/d
aprepitant
artesunate
-antimalarial
artesunate minocycline
-antibiotic
100 mg; 2×/d
minocycline
auranofin
-antirheumatic
auranofin auranofin
3 mg; 2×/d
auranofin
captopril
-antihypertensive
captopril captopril
50 mg; 2×/d
captopril
disulfiram-
alcohol deterrent
disulfiram disulfiram
250 mg; 2×/d
disulfiram
copper gluconate
-food supplement 2
celecoxib
-NSAID 3
celecoxib
400 mg; 2×/d
celecoxib
ketoconazole
-antifungal
itraconazole
-antifungal
itraconazole
200 mg; 2×/d
itraconazole
nelfinavir
-antiretroviral
ritonavir
-antiretroviral
ritonavir
400 mg; 2×/d
quetiapine
-atypical antipsychotic
25 mg; 1×/d
sertraline
-antidepressant
sertraline sertraline
100 mg; 2×/d
sertraline
temozolomide
-chemotherapeutic
temozolomide temozolomide
20 mg/m2; 2×/d
temozolomide

1 Previously referred to as CUSP9v4, 2 potential disulfiram enhancer, 3 non-steroidal anti-inflammatory drug.