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. 2021 Dec 16;13(12):2175. doi: 10.3390/pharmaceutics13122175

Table 2.

InPeps Ric1-Ric4 effects on the expression of genes related to gluconeogenesis and skeletal muscle contraction.

InPeps
Gene Name Symbol Control Insulin Ric 1 Ric 2 Ric 3 Ric 4
Peroxisome proliferator activator receptor gamma PPARγ 1 6.98 ± 1.23 ** 1.76 ± 1.03 2.03 ± 0.98 * 1.12 ± 0.72 1.21 ± 1.02
cAMP responsive element binding protein 1 Creb1 1 6.48 ± 1.08 ** 1.51 ± 1.01 0.96 ± 0.75 1.25 ± 0.94 1.03 ± 0.85
Aldolase A, fructose-bisphosphate ALDOA 1 7.65 ± 0.96 ** 3.81 ± 1.51 0.98 ± 1.53 1.01 ± 0.16 4.22 ± 0.74 **
Cytochrome c oxidase subunit IV isoform 1 Cox4i1 1 6.71 ± 1.24 ** 1.31 ± 0.87 1.42 ± 0.98 1.02 ± 1.21 1.41 ± 1.12
Phosphoglycerate mutase 2 PGAM2 1 8.26 ± 0.99 ** 4.05 ± 1.65* 1.03 ± 1.78 0.95 ± 0.57 2.65 ± 0.87 *
Troponin I, skeletal, fast 2 TNNI2 1 6.36 ± 1.13 ** 1.97 ± 1.16 0.98 ± 0.89 1.12 ± 1.01 3.14 ± 0.65 **
Troponin I, skeletal, fast 3 TNNT3 1 6.22 ± 0.98 ** 1.21 ± 1.17 3.08 ± 0.94 * 1.21 ± 1.11 2.38 ± 0.72 *
Small muscle protein X-linked SMPX 1 5.96 ± 0.98 ** 3.31 ± 1.67 * 1.05 ± 1.52 0.99 ± 0.32 3.21 ± 0.99 *
Myosin, light chain 1 MYL1 1 6.18 ± 1.07 ** 3.76 ± 1.24 * 1.15 ± 0.87 1.06 ± 0.39 3.58 ± 1.07 **

Footnote: * p < 0.05, ** p < 0.01; compared to control.