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. 2021 Dec 9;22(24):13260. doi: 10.3390/ijms222413260

Figure 2.

Figure 2

Characterization of TrkA and p75NTR expression in control and PSEN1 mutant neurons. Representative blots represent TrkA and p75NTR expression in PSEN1 mutant cultures compared to controls (A). IPSC lines: Ctrl-2, fAD-1; n = 6. Histograms demonstrate TrkA (A), p75NTR (B) expression in PSEN1 mutant neuronal cultures compared to controls and their ratio (C) (** p < 0.01). Images show TrkA (red) and p75NTR (green) expression in the cytoplasm and neurites of seven week old controls (Ctrl-2) and PSEN1 mutant neurons (fAD-1) (D). The data are expressed in optical densities (pixel/area) ± SEM. Scale bar = 20 µm, scale bar insert = 5 µm.