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. 2021 Dec 16;9(12):1490. doi: 10.3390/vaccines9121490

Table 4.

Examples of FDA-approved Virus-like Particle (VLP) vaccines.

Pathogen Vaccine Tradename Route of Administration Adjuvant Manufacturer
Human Papillomavirus Bivalent (Types 16 and 18) Vaccine CERVARIX® Intramuscular AS04 GlaxoSmithKline Biologicals. Brentford, United Kingdom
Human Papillomavirus Quadrivalent (Types 6, 11, 16, 18) Vaccine GARDASIL® Intramuscular Amorphous Aluminum Hydroxyphosphate Sulfate (AAHS) Merck & Co., Inc. Kenilworth, USA
Human Papillomavirus 9-valent Vaccine GARDASIL® 9 Intramuscular AAHS Merck & Co., Inc. Kenilworth, USA