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. 2021 Dec 14;57(12):1365. doi: 10.3390/medicina57121365

Table 3.

Univariate and multivariate analyses for systemic lymph node dissection.

Variables Univariate Multivariate
p Hazard Ratio (95% CI) p
Patient characteristics
 Age <0.01 * 1.02 (1.01–1.04) 0.17
 Male 0.55
 Pack-year 0.77
Carcinoembryonic antigen
 Level 0.76
Clinical N stage
 N1-2 <0.01 * 0.53 (0.36–0.79) <0.01 *
Histology
 Adenocarcinoma or SQCC 0.32
Procedures
 More than lobectomy <0.01 * 0.11 (0.04–0.30) <0.01 *
Approach
 Thoracotomy <0.01 * 1.87 (1.13–3.05) 0.01 *
Adjuvant
 Chemotherapy and/or radiotherapy <0.01 * 0.60 (0.42–0.86) <0.01 *
Pathological stage
 More advanced <0.01 * 1.14 (1.04–1.26) <0.01 *
Mutation status
EGFR or ALK positive <0.01 * 0.53 (0.38–0.75) <0.01 *

SQCC, squamous cell carcinoma; EGFR, epidermal growth factor receptor; ALK, anaplastic lymphoma kinase; CI, confidence index. p < 0.05, significant *.