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. 2021 Dec 7;13(12):873. doi: 10.3390/toxins13120873

Figure 4.

Figure 4

Ingenuity Pathway Analysis of differentially expressed genes regulated by lnc-SLC15A1-1. (A) Canonical pathways of differentially expressed genes regulated by lnc-SLC15A1-1. Vertical orange line indicates the default threshold. The gray bars indicate no activity pattern. (B) Representative network of downstream genes regulated by lnc-SLC15A1-1. Red and blue stars indicate CXCL10 and CXCL8, respectively. Green color indicates downregulation, and red color indicate upregulation. Solid lines represent direct interaction (yellow), and dashed lines represent indirect interaction. Various shapes representing the functional class of the gene product. (C) Quantitative RT-PCR analyses of top 10 differentially expressed genes identified by microarray. Loading control: GAPDH. Experiments were repeated in triplicate, and the results are the mean ± SDs. (* p < 0.05).