Table 3.

Inhibition of related glutaminyl cyclases from bacteria and human and cytotoxicity of selected inhibitors.

	8k	8t	8w
Ki (µM)
PiQC	0.063 ± 0.007	0.096 ± 0.012	0.117 ± 0.002
TfQC	0.176 ± 0.003	0.221 ± 0.019	0.185 ± 0.010
hQC	0.387 ± 0.064	0.385 ± 0.096	0.132 ± 0.011
Cell viability @ 30 µM (%)
SHSY-5Y	119	128	127
Hep-G2	92	96	94