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. 2021 Nov 24;19(12):659. doi: 10.3390/md19120659

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The threshold to induce sustained ventricular fibrillation (VF) is lower in male (A) and female (B) spontaneously hypertensive rat (SHR) hearts than normotensive rats (WR). The VF threshold was significantly reduced after 6-week continuous light in WR and SHR males but not in females of either strain. Treatment with Omacor^® increased the electrical threshold for induced sustained VF in males of both rat strains. The values here are the mean ± SD of 6 rats in each group. * p < 0.05 compared to WR; # p < 0.05 compared to SHR; ♣ p < 0.05 compared to SHR-L.