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Lymphocytic infiltration of the salivary gland in SS and potential therapeutic targets
T-cell help is required to form ectopic lymphoid structures (ELS) in the salivary gland. Strategies to treat SS include: a direct effect on B-cells, B-cell activating factor (BAFF), its receptor (BAFF-R) or co-stimulation molecules. BAFF: B-cell activating factor, BAFF-R: B-cell activating factor receptor. Created with BioRender.com.
