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. 2021 Dec 1;23(1):50–61. doi: 10.1038/s41590-021-01084-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a, Frequency of convalescent patients with COVID-19 (n = 52 total patient cohort, n = 19 HLA-B*07:02-positive patients only) with T cells responding to NP_105–113-B*07:02 epitope stimulation. b, Frequency of HLA-B*07:02-positive responders (n = 15) and nonresponders (n = 4) with mild or severe COVID-19 disease. c, Comparison of the magnitude of the response to the NP_105–113 epitope between HLA-B*07:02-positive convalescent patients with COVID-19 (n = 10 mild, n = 9 severe). d, Proportion of NP_105-113-specific response to overall NP response (n = 10 mild, n = 9 severe). e, Proportion of HLA-B*07:02 individuals compared with combined total acute and convalescent COVID-19 patients (n = 77 acute, n = 52 convalescent). Data are presented as medians with interquartile ranges (IQRs) (c and d). The Mann–Whitney U-test was used for analysis and the two-tailed P value was calculated: *P < 0.05. s.f.u., spot-forming units.