Fig. 3. Paired αβ TCR repertoire of NP_105–113-B*07:02-specific T cells from convalescent patients with COVID-19.

a, Circos plots for each patient depicting αβ VJ gene usage: two patients with mild disease (C-COV19-005 and C-COV19-046) and two with severe symptoms (C-COV19-045 and C-COV19-038). b, Circos plot to show TCR clonotypes for all patients (clonotype defined as patient-specific V-gene usage and CDR3 amino acid sequence for Vα and Vβ). Each line represents a unique clonotype. Clonotypes that have dominant Vβ gene usage (TRBV5-1, TRBV28, TRBV27 and TRBV24) are highlighted; all others are shown in gray.