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. 2021 Dec 1;23(1):50–61. doi: 10.1038/s41590-021-01084-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 1 — (a) Distribution of age, gender and days post symptom onset when sampling of SARS-CoV-2 infected patients. (b) and (c) Comparison of age (ns, P = 0.116) and days post symptom (ns, P = 0.5711) when sampling between the patient groups with mild and severe symptoms. Unpaired t-test with Welch’s correction and Mann-Whitney test were used for data analysis of (B) and (C) respectively. Two tailed P value was calculated. (d) Breakdown of patient numbers and severity; HLA-B*07:02 negative (mild N = 20 light grey, N = 13 dark grey); HLA-B*07:02 positive responders (mild N = 9 red, severe N = 6 blue); HLA-B*07:02 positive non-responders (mild N = 1 light red, severe N = 3 light blue).