Table 2.
Patient characteristics
| Characteristic | Content validation cohort (N = 23) | Psychometric evaluation | Exit interview cohort (N = 70) | |
|---|---|---|---|---|
| Phase 2 cohort (N = 174) | Pooled phase 3 cohort (N = 848) | |||
| Age (years) | ||||
| Mean (SD) | 55.4 (17.0) | 57.3 (12.5) | 58.7 (12.9) | 55.7 (12.1) |
| Median [range] | 61.0 [25.0–82.0] | 59.0 [26.0–84.0] | 59.0 [22.0–88.0] | 57.0 [24.0–79.0] |
| Gender, n (%) | ||||
| Male | 14 (60.9) | 105 (60.3) | 504 (59.4) | 46 (65.7) |
| Female | 9 (39.1) | 69 (39.7) | 344 (40.6) | 24 (34.3) |
| Race, n (%) | ||||
| White | 10 (43.5) | 62 (35.6) | 515 (60.7) | 42 (60.0) |
| Black or African American | 6 (26.1) | 102 (58.6) | 248 (29.2) | 20 (28.6) |
| Asian | 1 (4.3) | 4 (2.3) | 45 (5.3) | 3 (4.3) |
| American Indian or Alaskan native | 1 (4.3) | 4 (2.3) | 13 (1.5) | 1 (1.4) |
| Native Hawaiian or other Pacific Islander | 0 (0.0) | 1 (0.6) | 10 (1.2) | 2 (2.9) |
| Other | 8 (34.8) | 0 (0.0) | 14 (1.7) | 2 (2.9) |
| Not reported | 0 (0.0) | 1 (0.6) | 3 (0.4) | 0 (0.0) |
| Ethnicity, n (%) | ||||
| Not Hispanic or Latino | 15 (65.2) | 136 (78.2) | 572 (67.5) | 32 (45.7) |
| Hispanic or Latino | 8 (34.8) | 36 (20.7) | 268 (31.6) | 38 (54.3) |
| Not reported | 0 (0.0) | 2 (1.1) | 8 (0.9) | 0 (0.0) |
| Years on hemodialysis mean (SD) | 5.4 (5.1) | 5.8 (4.7) | 4.8 (4.3) | 3.3 (2.3) |
| Years with CKD-aP, mean (SD) | 2.9 (3.0) | 4.4 (4.1) | 3.3 (3.7) | 2.7 (2.1) |
| Baseline WI-NRS, n (%) | ||||
| ≥ 0 to < 4 | 3 (13.0) | – | – | – |
| ≥ 4 to < 6 | 3 (13.0) | 51 (29.3) | 187 (22.1) | 7 (10.0) |
| ≥ 6 to < 8 | 11 (47.8) | 81 (46.6) | 384 (45.3) | 34 (48.6) |
| ≥ 8 to 10 | 6 (26.1) | 42 (24.1) | 277 (32.7) | 29 (41.4) |
SD, Standard deviation