Table 3.
Echocardiography, pulmonary function and cardiopulmonary exercise test at follow-up
| Parameter (n) | Mean ± SD | Range (min.–max.) |
|---|---|---|
| Echocardiography (20 patients) | ||
| Right atrial area, cm2 | 16.0 ± 3.6 | 8.0–22.0 |
| RVEDD, mm | 32.9 ± 5.6 | 22.0–44.0 |
| TAPSE, mm | 23.2 ± 5.8 | 17.0–38.0 |
| Systolic PAP, mmHg (15 patients) | 19.3 ± 4.8 | 13.0–30.0 |
| Pulmonary function test and capillary blood gas analysis (20 patients) | ||
| Vital capacity, % predicted | 83.1 ± 16.1 | 51.0–105.0 |
| FEV1, % predicted | 80.5 ± 19.8 | 33.0–105.0 |
| DLCO, % predicted | 73.1 ± 22.1 | 30.0–97.0 |
| pCO2, mmHg | 36.0 ± 4.0 | 28.8–42.7 |
| Oxygen saturation, % on room air | 95.8 ± 1.5 | 94.0–98.0 |
| Cardiopulmonary exercise test (13 patients) | ||
| Maximum work rate, W | 125.8 ± 52.8 | 52.0–221.0 |
| Maximum work rate, % predicted | 82.8 ± 23.1 | 41.0–118.0 |
| Peak-VO2, ml × min−1 × kg−1 | 19.2 ± 8.3 | 9.3–34.0 |
| Peak-VO2, % predicted | 76.3 ± 16.1 | 44.0–102.0 |
| RER max. | 1.4 ± 0.2 | 1.1–1.9 |
| Breathing reserve, % | 44.4 ± 14.5 | 21.0–70.0 |
| VE/VCO2 slope | 28.7 ± 4.9 | 19.5–39.1 |
| ∆VO2/∆WR slope, ml × min−1 × W−1 | 9.6 ± 1.0 | 7.1–11.2 |
| P(a-ET)CO2, mmHg | 4.5 ± 2.0 | 0.3–6.9 |
| AaDO2, mmHg | 29.2 ± 7.0 | 19.9–40.1 |
AaDO2 alveolar–arterial difference in partial pressures of oxygen; DLCO diffusion capacity of the lung for carbon monoxide; FEV1 forced end-expiratory volume in one second; PAP pulmonary arterial pressure; P(a-ET)CO2 arterial to end-tidal difference in partial pressures of CO2; RER respiratory exchange rate; RVEDD right ventricular end-diastolic diameter; TAPSE tricuspid anterior plane systolic excursion