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. 2021 Dec 24;11:24413. doi: 10.1038/s41598-021-03993-3

Table 2.

Details of competing endogenous RNA (ceRNA) axes.

DElncRNA(s) Shared miRNA(s) DEmRNA(s) Sample Expression of DElncRNA(s) and DEmRNA(s)
DLX6-AS1 hsa-miR-22-3p ACVR1C, BDNF HPC Down
DLX6-AS1

hsa-miR-124-3p

hsa-miR-132-3p

hsa-miR-15a-5p

BDNF HPC Down
DLX6-AS1 hsa-miR-708-5p NNAT HPC Down
BABAM2-AS1, NEAT1, LINC01094 hsa-miR-30b-5p BCL6 HPC Up
NEAT1 hsa-miR-9-5p BCL6, TGFBI, TGFBR2 HPC Up
LINC01094, NEAT1 hsa-miR-132-3p CDKN1A HPC Up
NEAT1 hsa-miR-22-3p CDKN1A HPC Up
BABAM2-AS1, LINC01094, NEAT1 hsa-miR-17-5p CDKN1A, TGFBR2, VEGFA HPC Up
NEAT1, LINC01094 hsa-miR-29a-3p FGG, TET1, VEGFA, ZFP36, TNFAIP3, MCL1, CD93 HPC Up
LINC01094, NEAT1 hsa-miR-7-5p FOS HPC Up
NEAT1, LINC01094 hsa-miR-29c-3p MCL1, FGG, VEGFA HPC Up
LINC01094, MINCR, NEAT1 hsa-miR-23a-3p MT2A, HMGB2 HPC Up
NEAT1 hsa-miR-126-3p NFKBIA, PIK3R2, ADM, VEGFA HPC Up
PAX8-AS1, LINC01094, NEAT1 hsa-miR-29b-3p TET1, FOS, ANGPTL4, AQP4, FGG, VEGFA, TNFAIP3, MCL1 HPC Up
BABAM2-AS1, PAX8-AS1, LINC01094, NEAT1 hsa-miR-20b-5p VEGFA, CDKN1A HPC Up
LINC01094, NEAT1 hsa-miR-195-5p VEGFA, FGF2 HPC Up
NEAT1, DLGAP1-AS1 hsa-miR-15a-5p VEGFA, IL10RA, HSPA1B HPC Up
PAX8-AS1, LINC01094, NEAT1, MINCR hsa-miR-34a-5p VEGFA, NAMPT, FOS, CD44 HPC Up
NEAT1 hsa-miR-126-5p VEGFA HPC Up
NEAT1, LINC01094, DLGAP1-AS1 hsa-miR-15b-5p VEGFA HPC Up
NEAT1 hsa-miR-126-3p ADM, SOX2, VEGFA, MERTK, NFKBIA BA46 Up
NEAT1, LINC01094 hsa-miR-30b-5p BCL6, CAT BA46 Up
NEAT1 hsa-miR-22-3p CDKN1A, BMPR1B BA46 Up
LINC01094, NEAT1 hsa-miR-132-3p CDKN1A BA46 Up
NEAT1, LINC01094 hsa-miR-17-5p CDKN1A, VEGFA BA46 Up
PAX8-AS1, LINC01094, NEAT1 hsa-miR-20b-5p CDKN1A, VEGFA BA46 Up
NEAT1 hsa-miR-138-5p FERMT2, VIM, YAP1 BA46 Up
ZFHX4-AS1, LINC01094, NEAT1 hsa-miR-7-5p FOS BA46 Up
NEAT1, MINCR, LINC01094, ZFHX4-AS1 hsa-miR-23a-3p HMGB2, MT2A BA46 Up
NEAT1, LINC01094 hsa-miR-29a-3p MCL1, ZFP36, TET1, FGG, VEGFA, TNFAIP3, CD93 BA46 Up
NEAT1, PAX8-AS1, MINCR, LINC01094 hsa-miR-98-5p NRAS BA46 Up
MINCR, PAX8-AS1, LINC01094, ZFHX4-AS1, NEAT1 hsa-miR-34a-5p SOX2, VEGFA, NAMPT, CD44, FOS BA46 Up
NEAT1, PAX8-AS1, LINC01094, MINCR hsa-let-7 g-5p TGFBR1 BA46 Up
LINC01094, NEAT1 hsa-miR-15b-5p VEGFA BA46 Up
LINC01094, PAX8-AS1, NEAT1 hsa-miR-29b-3p VEGFA, MCL1, ELAVL1, TNFAIP3, FOS, FGG, AQP4, ANGPTL4, TET1 BA46 Up
NEAT1, LINC01094 hsa-miR-29c-3p VEGFA, MCL1, FGG BA46 Up
NEAT1 hsa-miR-126-5p VEGFA BA46 Up
ZFHX4-AS1, NEAT1 hsa-miR-9-5p VIM, BCL6, ELAVL1, TGFBI BA46 Up
NEAT1, MINCR hsa-miR-124-3p VIM BA46 Up
NEAT1, LINC01094 hsa-miR-195-5p YAP1, VEGFA, FGF2 BA46 Up
NEAT1 hsa-miR-15a-5p YAP1, VEGFA, IL10RA, UCP2, HSPA1B BA46 Up
DLX6-AS1 hsa-miR-34a-5p EPHA5 STR Down
NEAT1 hsa-miR-126-3p ADM, VEGFA, NFKBIA, PIK3R2 STR Up
LINC01094, NEAT1 hsa-miR-30b-5p BCL6 STR Up
NEAT1 hsa-miR-22-3p CDKN1A STR Up
NEAT1, LINC01094 hsa-miR-132-3p CDKN1A STR Up
MINCR, LINC01094, NEAT1 hsa-miR-23a-3p FAS, HMGB2 STR Up
NEAT1, LINC01094 hsa-miR-7-5p FOS STR Up
LINC01094, MINCR, PAX8-AS1, NEAT1 hsa-miR-34a-5p FOS, VEGFA, NAMPT, CD44 STR Up
LINC01094, NEAT1 hsa-miR-29a-3p MCL1, VEGFA, TNFAIP3, CD93, SPARC, ZFP36, FGG STR Up
MINCR, PAX8-AS1, LINC01094, NEAT1 hsa-let-7 g-5p TGFBR1 STR Up
DLGAP1-AS1, NEAT1 hsa-miR-15a-5p UCP2, VEGFA, IL10RA, HSPA1B, YAP1 STR Up
NEAT1, LINC01094 hsa-miR-17-5p VEGFA, CDKN1A STR Up
PAX8-AS1, NEAT1, LINC01094 hsa-miR-20b-5p VEGFA, CDKN1A STR Up
DLGAP1-AS1, LINC01094, NEAT1 hsa-miR-15b-5p VEGFA STR Up
LINC01094, PAX8-AS1, NEAT1 hsa-miR-29b-3p VEGFA, MCL1, ELAVL1, SPARC, ANGPTL4, AQP4, FGG, FOS, TNFAIP3 STR Up
LINC01094, NEAT1, XIST hsa-miR-29c-3p VEGFA, MCL1, FGG, SPARC STR Up
NEAT1 hsa-miR-126-5p VEGFA STR Up
LINC01094, NEAT1 hsa-miR-195-5p VEGFA, YAP1, FGF2 STR Up
NEAT1 hsa-miR-9-5p VIM, ELAVL1, BCL6, TGFBI STR Up
NEAT1, MINCR hsa-miR-124-3p VIM STR Up
NEAT1 hsa-miR-138-5p VIM, YAP1 STR Up
MALAT1 hsa-miR-9-5p STARD13 LB Up

Bold values are common ceRNA axes between all three areas of the brain.

BA46 Brodmann area 46, DElncRNAs differentially expressed lncRNAs, DEmRNAs differentially expressed mRNAs, down downregulation, HPC hippocampus, LB lymphoblast, STR striatum, up upregulation.