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. Author manuscript; available in PMC: 2024 Feb 1.
Published in final edited form as: Ann Surg. 2023 Jan 10;277(2):e294–e304. doi: 10.1097/SLA.0000000000005027

Table 2.

30-, 90-, and 180-day Mortality Grouped by Frailty and Expanded Operative Stress Score

Mortality OSS1 OSS2 OSS3 OSS4 OSS5
n=2,516 n=30,725 n= 38,820 n=8,710 n=1,498
30-day Deaths, No.   10  183  614  381  79
30-day Mortality by RAI % (95% CI)
 Robust (≤20) 0.06 (0.00–0.31) 0.14 (0.09–0.20) 0.32 (0.25–0.40) 1.83 (1.43–2.31) 2.12 (1.02–3.87)
 Normal (21–29) 0.36 (0.04–1.28) 0.96 (0.75–1.20) 2.09 (1.83–2.38) 5.10 (4.37–5.92) 6.78 (5.19–8.68)
 Frail (30–39) 3.38 (1.11–7.71) 5.10 (3.93–6.51) 8.44 (7.45–9.53) 6.95 (5.72–8.36) 7.10 (3.60–12.34)
 Very Frail (≥40) 11.11 (1.38–34.71) 14.63 (8.91–22.14) 18.39 (14.46–22.87) 27.15 (20.24–34.98) 0.00 (0.00–19.51)
 Overall Mortality 0.40 (0.19–0.73) 0.60 (0.51–0.69) 1.58 (1.46–1.71) 4.37 (3.95–4.83) 5.27 (4.20–6.53)
90-day Deaths, No.   20  300  917  541  106
Mortality by RAI, % (95% CI)
 Robust (≤20) 0.11 (0.01–0.40) 0.23 (0.17–0.30) 0.48 (0.40–0.58) 2.36 (1.90–2.89) 2.97 (1.63–4.94)
 Normal (21–29) 0.36 (0.04–1.28) 1.50 (1.24–1.80) 3.12 (2.80–3.46) 7.21 (6.34–8.15) 8.77 (6.96–10.87)
 Frail (30–39) 9.46 (5.27–15.36) 8.62 (7.09–10.36) 12.79 (11.58–14.07) 10.79 (9.27–12.47) 10.97 (6.52–16.98)
 Very Frail (≥40) 11.11 (1.38–34.71) 26.02 (18.52–34.70) 25.57 (21.07–30.50) 36.42 (28.75–44.64) 0.00(0.00–19.51)
 Overall Mortality 0.79 (0.49–1.23) 0.98 (0.87–1.09) 2.36 (2.21–2.52) 6.21 (5.71–6.74) 7.08 (5.83–8.49)
180-day Deaths, No.   26  434  1186  677  160
Mortality by RAI, % (95% CI)
 Robust (≤20) 0.17 (0.03–0.49) 0.35 (0.27–0.43) 0.67 (0.57–0.78) 2.83 (2.33–3.41) 5.31 (3.46–7.74)
 Normal (21–29) 0.53 (0.11–1.55) 2.15 (1.84–2.50) 4.12 (3.76–4.51) 8.78 (7.83–9.81) 12.28 (10.16–14.67)
 Frail (30–39) 12.16 (7.37–18.54) 12.55 (10.73–14.57) 16.08 (14.75–17.48) 14.64 (12.89–16.52) 18.06 (12.35–25.04)
 Very Frail (≥40) 11.11 (1.38–34.71) 34.96 (26.58–44.08) 31.03 (26.21–36.19) 42.38 (34.39–50.68) 11.76 (1.46–36.44)
 Overall Mortality 1.03 (0.68–1.51) 1.41 (1.28–1.55) 3.06 (2.89–3.23) 7.77 (7.22–8.35) 10.68 (9.16–12.36)

Abbreviations: CI, Confidence Interval; OSS, Operative Stress Score; RAI, Risk Analysis Index

Graham-Mengersen-Morton tests were used to calculate 95% confidence intervals.