Table 4.

PASC and 30-day Complications Odds Ratios Adjusted for Sex, RAI, OSS and Case Status

	Adjusted OR (95% CI)	P value
PASC
Male (Ref = Female)	1.31 (1.21–1.41)	<.001
RAI (Ref = Normal 21–29)
Robust (≤20)	0.60 (0.55–0.66)	<.001
Frail (30–39)	1.46 (1.31–1.63)	<.001
Very frail (≥40)	2.41 (1.97–2.95)	<.001
Expanded OSS (Ref = OSS1)
OSS2	0.71 (0.59–0.87)	.001
OSS3	0.71 (0.58–0.86)	.001
OSS4	2.24 (1.83–2.74)	<.001
OSS5	0.57 (0.39–0.85)	.005
Urgent/Emergent (Ref = elective)	19.08 (17.19–21.16)	<.001
Model C-Statistic	0.87
No complications
Male (Ref = Female)	1.07 (1.02–1.11)	.003
RAI (Ref = Normal 21–29)
Robust (≤20)	1.75 (1.68–1.84)	<.001
Frail (30–39)	0.64 (0.60–0.68)	<.001
Very frail (≥40)	0.39 (0.33–0.46)	<.001
Expanded OSS (Ref = OSS1)
OSS2	0.87 (0.74–1.03)	.11
OSS3	0.37 (0.32–0.43)	<.001
OSS4	0.12 (0.11–0.15)	<.001
OSS5	0.06 (0.05–0.07)	<.001
Urgent/Emergent (Ref = elective)	0.40 (0.38–0.42)	<.001
Model C-Statistic	0.75
Any complication
Male (Ref = Female)	0.94 (0.90–0.98)	.003
RAI (Ref = Normal 21–29)
Robust (≤20)	0.57 (0.54–0.60)	<.001
Frail (30–39)	1.56 (1.46–1.67)	<.001
Very frail (≥40)	2.56 (2.16–3.02)	<.001
Expanded OSS (Ref = OSS1)
OSS2	1.14 (0.97–1.35)	.11
OSS3	2.71 (2.31–3.18)	<.001
OSS4	8.10 (6.88–9.55)	<.001
OSS5	16.70 (13.82–20.19)	<.001
Urgent/Emergent (Ref = elective)	2.51 (2.41–2.62)	<.001
Model C-Statistic	0.75
Clavien-Dindo IV complications
Male (Ref = Female)	1.18 (1.09–1.28)	<.001
RAI (Ref = Normal 21–29)
Robust (≤20)	0.40 (0.36–0.44)	<.001
Frail (30–39)	1.44 (1.29–1.61)	<.001
Very frail (≥40)	2.00 (1.61–2.50)	<.001
Expanded OSS (Ref = OSS1)
OSS2	1.21 (0.81–1.80)	0.35
OSS3	3.17 (2.16–4.67)	<.001
OSS4	7.26 (4.92–10.72)	<.001
OSS5	13.78 (9.10–20.86)	<.001
Urgent/Emergent (Ref = elective)	4.50 (4.14–4.89)	<.001
Model C-Statistic	0.81

Abbreviations: OR, Odds Ratio; RAI, Risk Analysis Index; OSS, Operative Stress Score; PASC, Preoperative Acute Serious Conditions; Ref, reference

Logistic regression analyses