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. 2021 Dec 8;134(24):2999–3008. doi: 10.1097/CM9.0000000000001563

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Copyright © 2021 The Chinese Medical Association, produced by Wolters Kluwer, Inc. under the CC-BY-NC-ND license.

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The knockdown of PDPN suppressed TSCC development. The cells were transfected with si-PDPN. (A): A CCK-8 assay was performed to assess the viability of CAL-27 and CTSC-3 cells. (B) A cell adhesion assay was performed to evaluate the adhesive ability of CAL-27 and CTSC-3 cells. (C): A wound-healing assay was performed to detect the migratory ability of CAL-27 and CTSC-3 cells. CCK-8: Cell counting kit-8; CON: Blank control group; NC: Negative control; OD: Optical density; PDPN: Podoplanin; TSCC: Tongue squamous cell carcinoma. ^∗P < 0.001 vs. the blank control group.