Figure 3. Selection of the immunized mouse producing anti-Siglec-15 mAb. (A) Serum titer of Balb/c mice immunized by Freund’s complete adjuvant. (B) Serum titer of Balb/c mice immunized by water-soluble adjuvant. The number behind F and W denotes the mouse number in the experiments. All the mice were administered 5 times by Siglec-15-mIgG. * denotes p compared between different mice (*P<0.05, ** P<0.01, *** P<0.001, n=5).
