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. 2021 Dec 13;12:741484. doi: 10.3389/fimmu.2021.741484

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Copyright © 2021 Hortová-Kohoutková, De Zuani, Lázničková, Bendíčková, Mrkva, Andrejčinová, Mýtniková, Polanský, Kočí, Tomášková, Šrámek, Helán and Frič

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Biological functions and biomarker analysis of the most expressed proteins. (A) Proteins were analyzed by the STRING web tool to reveal their possible interactions and their association with specific biological processes. The line thickness between each node indicates the strength of the data support. (B) ROC curve analysis was performed to evaluate the potential to predict five-day survival. Alpha-enolase, annexin A3, vimentin, and lysozyme C showed the significant predictive potential of early death from septic shock.