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. 2021 Dec 13;8:780605. doi: 10.3389/fcvm.2021.780605

Table 4.

Microvascular function data.

Flow (Perfusion Units, in mV) P
Treatment group
Clopidogrel (n = 20) Prasugrel (n = 15) Ticagrelor (n = 21)
Median IQR Median IQR Median IQR
Screening 44 28–74 39 27–68 61 20–135
Resting 0.440
Peak during Hyperemia 119 71–173 108 64–146 124 84–197 0.363
% PORH 156 65–229 146 86–224 88 40–265 0.502
After oral loading 45 29–83 29 19–48 50 19–116
Resting 0.158
Peak during Hyperemia 111 75–160 112 64–148 133 73–198 0.572
% PORH 140* 70–180 216* 159–457 159* 58–342 0.022**
1 day after stenting 59 40–80 31 23–52 40 25–82
Resting 0.091
Peak during Hyperemia 138 89–179 102 66–136 92 84–172 0.437
% PORH 101 47–177 110 82–303 139 95–264 0.287
1 week after stenting 30 17–60 49 20–75 33 21–75
Resting 0.490
Peak during Hyperemia 94 81–135 116 88–192 120 67–173 0.599
% PORH 193 113–327 135 86–298 224 90–352 0.726
1 Month after stenting 49 27–81 57 30–71 57 26–95
Resting 0.609
Peak during Hyperemia 119 96–140 119 91–130 134 9–175 0.436
% PORH 152 46–233 106 100–184 125 65–175 0.894
*

: P = 0.015 among groups for the change in %PORH between screening and following oral loading (P = 0.007 for the comparison clopidogrel vs. prasugrel; P = 0.329 for the comparison prasugrel vs. ticagrelor and P = 0.042 for the comparison clopidogrel vs. ticagrelor);

**

: P = 0.003 for the comparison prasugrel vs. clopidogrel, P = 0.117 for the comparison prasugrel vs. ticagrelor, P = 0.415 for the comparison clopidogrel vs. ticagrelor;

= 0.026 for the comparison with immediately after loading.