Table 4.
Flow (Perfusion Units, in mV) | P | ||||||
---|---|---|---|---|---|---|---|
Treatment group | |||||||
Clopidogrel (n = 20) | Prasugrel (n = 15) | Ticagrelor (n = 21) | |||||
Median | IQR | Median | IQR | Median | IQR | ||
Screening | 44 | 28–74 | 39 | 27–68 | 61 | 20–135 | |
Resting | 0.440 | ||||||
Peak during Hyperemia | 119 | 71–173 | 108 | 64–146 | 124 | 84–197 | 0.363 |
% PORH | 156 | 65–229 | 146 | 86–224 | 88 | 40–265 | 0.502 |
After oral loading | 45 | 29–83 | 29 | 19–48 | 50 | 19–116 | |
Resting | 0.158 | ||||||
Peak during Hyperemia | 111 | 75–160 | 112 | 64–148 | 133 | 73–198 | 0.572 |
% PORH | 140* | 70–180 | 216* | 159–457 | 159* | 58–342 | 0.022** |
1 day after stenting | 59 | 40–80 | 31 | 23–52 | 40 | 25–82 | |
Resting | 0.091 | ||||||
Peak during Hyperemia | 138 | 89–179 | 102 | 66–136 | 92 | 84–172 | 0.437 |
% PORH | 101 | 47–177 | 110† | 82–303 | 139 | 95–264 | 0.287 |
1 week after stenting | 30 | 17–60 | 49 | 20–75 | 33 | 21–75 | |
Resting | 0.490 | ||||||
Peak during Hyperemia | 94 | 81–135 | 116 | 88–192 | 120 | 67–173 | 0.599 |
% PORH | 193 | 113–327 | 135 | 86–298 | 224 | 90–352 | 0.726 |
1 Month after stenting | 49 | 27–81 | 57 | 30–71 | 57 | 26–95 | |
Resting | 0.609 | ||||||
Peak during Hyperemia | 119 | 96–140 | 119 | 91–130 | 134 | 9–175 | 0.436 |
% PORH | 152 | 46–233 | 106 | 100–184 | 125 | 65–175 | 0.894 |
: P = 0.015 among groups for the change in %PORH between screening and following oral loading (P = 0.007 for the comparison clopidogrel vs. prasugrel; P = 0.329 for the comparison prasugrel vs. ticagrelor and P = 0.042 for the comparison clopidogrel vs. ticagrelor);
: P = 0.003 for the comparison prasugrel vs. clopidogrel, P = 0.117 for the comparison prasugrel vs. ticagrelor, P = 0.415 for the comparison clopidogrel vs. ticagrelor;
= 0.026 for the comparison with immediately after loading.