Table 5. Comparison of clinical and economic primary outcomes.
Outcomes | Low dose of rehabilitation (mean rats <3.6), n=27 | High dose of rehabilitation (mean rats >3.6), n=27 | P-value | Adjusted P-value |
Primary outcome | ||||
ADL dependence at discharge, n (%) | 22 (81) | 6 (22) | <0.001 | <0.001 |
Secondary outcomes | ||||
Clinical outcomes and physical assessment | ||||
Total medical costs (US dollars), median [IQR] | 26335 [19726–39603] | 28042 [16935–40410] | 0.993 | 0.976 |
Duration of mechanical ventilation (days), median [IQR] | 6 [5–9] | 4 [2–6] | 0.007 | 0.076 |
ICU length of stay (days), median [IQR] | 8 [6–9] | 7 [6–11] | 0.931 | 0.905 |
Hospital length of stay (days), median [IQR] | 33 [27–43] | 28 [22–56] | 0.539 | 0.658 |
Discharge to home, n (%) | 15 (56) | 18 (67) | 0.402 | 0.299 |
Hospital survival, n (%) | 27 (100) | 24 (89) | 0.236 | 0.999 |
ICU-AW at ICU discharge, n (%) | 19 (70) | 10 (37) | 0.028 | 0.016 |
Delirium during ICU stay, n (%) | 8 (30) | 4 (15) | 0.327 | 0.130 |
Rehabilitation in ICU and Ward | ||||
Time to first rehabilitation from the ICU admission (days) | 2 [1–3] | 2 [1–3] | 0.473 | 0.529 |
Time to first meet the criteria for mobilization from the ICU admission (days) | 6 [5–7] | 4 [3–6] | 0.006 | <0.001 |
Time to first out of bed mobilization from the ICU admission (days) | 8 [5–9] | 4 [3–7] | 0.014 | 0.058 |
The highest ICU mobility scale during ICU stay (score) | 1 [1–3] | 7 [5–10] | <0.001 | <0.001 |
Achieved mobilization within 7 days from the ICU admission | 10 (37) | 21 (78) | 0.005 | 0.002 |
Number of daily rehabilitation sessions per person during ward care | 1 [1–1] | 1 [1–1] | 0.256 | 0.298 |
Data are presented as median [interquartile range] or number (%).
ICU-AW, intensive care unit acquired weakness.