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. 2021 Dec 29;6:20210054. doi: 10.2490/prm.20210054

Table 5.  Comparison of clinical and economic primary outcomes.

Outcomes Low dose of rehabilitation (mean rats <3.6), n=27 High dose of rehabilitation (mean rats >3.6), n=27 P-value Adjusted
P-value
Primary outcome
ADL dependence at discharge, n (%) 22 (81) 6 (22) <0.001 <0.001
Secondary outcomes
Clinical outcomes and physical assessment
 Total medical costs (US dollars), median [IQR] 26335 [19726–39603] 28042 [16935–40410] 0.993 0.976
 Duration of mechanical ventilation (days), median [IQR] 6 [5–9] 4 [2–6] 0.007 0.076
 ICU length of stay (days), median [IQR] 8 [6–9] 7 [6–11] 0.931 0.905
 Hospital length of stay (days), median [IQR] 33 [27–43] 28 [22–56] 0.539 0.658
 Discharge to home, n (%) 15 (56) 18 (67) 0.402 0.299
 Hospital survival, n (%) 27 (100) 24 (89) 0.236 0.999
 ICU-AW at ICU discharge, n (%) 19 (70) 10 (37) 0.028 0.016
 Delirium during ICU stay, n (%) 8 (30) 4 (15) 0.327 0.130
Rehabilitation in ICU and Ward
 Time to first rehabilitation from the ICU admission (days) 2 [1–3] 2 [1–3] 0.473 0.529
 Time to first meet the criteria for mobilization from the ICU admission (days) 6 [5–7] 4 [3–6] 0.006 <0.001
 Time to first out of bed mobilization from the ICU admission (days) 8 [5–9] 4 [3–7] 0.014 0.058
 The highest ICU mobility scale during ICU stay (score) 1 [1–3] 7 [5–10] <0.001 <0.001
 Achieved mobilization within 7 days from the ICU admission 10 (37) 21 (78) 0.005 0.002
 Number of daily rehabilitation sessions per person during ward care 1 [1–1] 1 [1–1] 0.256 0.298

Data are presented as median [interquartile range] or number (%).

ICU-AW, intensive care unit acquired weakness.