Table 3.
Key targets of AS antioxidant PPI network.
| Number | Target | Degree | Number | Target | Degree |
|---|---|---|---|---|---|
| 1 | Threonine kinase1 (AKT1) | 106 | 2 | Interleukin 6 (IL-6) | 87 |
| 3 | Mitogen-activated protein kinase 3 (MAPK3) | 81 | 4 | Mitogen-activated protein kinase 1 (MAPK1) | 79 |
| 5 | Tumor necrosis factor (TNF) | 78 | 6 | Epidermal growth factor receptor (EGFR) | 73 |
| 7 | SRC proto-oncogene (SRC) | 70 | 8 | Signal transducer and activator of transcription 3 (STAT3) | 66 |
| 9 | Mitogen-activated protein kinase 8 (MAPK8) | 66 | 10 | C-X-C motif chemokine ligand 8 (CXCL8) | 64 |
| 11 | Sirtuin-1 (SIRT1) | 64 | 12 | Prostaglandin-endoperoxide synthase 2 (PTGS2) | 64 |
| 13 | Mechanistic target of rapamycin kinase (MTOR) | 59 | 14 | Strogen receptor 1 (ESR1) | 58 |