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. 2021 Dec 13;12:718147. doi: 10.3389/fphar.2021.718147

FIGURE 12.

FIGURE 12

Neuropathologic scoring (0–8), cerebral cortex, cerebellar cortex, hypothalamus, hippocampus, and the number of karyopyknotic cells, cerebral cortex, cerebellar cortex, hypothalamus, hippocampus, in the thiopental-anesthetized rats with the increased intra-abdominal pressures at 50 mmHg for 25 min, at 30 mmHg or 40 mmHg for 30 min, at 25 mmHg for 60 min increased intra-abdominal pressures-time, and in the esketamine-anesthetized rats with the increased intra-abdominal pressures at the 25 mmHg at the 120 min increased intra-abdominal pressures-time, following medication (BPC 157 10 μg/kg (light gray bars), 10 ng/kg (dark gray bars); saline 5 ml/kg (white bars)) given subcutaneously at 10 min increased intra-abdominal pressures-time. Minimum (min), maximum (max), median (med), means ± SD, *P˂0.05, vs. control.