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Immunohistochemistry. In 5/6Nx rats, fibrin-associated protein marks in kidney tissue of 5/6 nephrectomy rats were significantly increased, and rhubarb enema could reduce the expression of these markers (The brown-black area means the immunohistochemical positive area). FN, fibronectin. α-SMA, alpha smooth muscle actin. Col-I, collagen- I (400×).
