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. 2021 Dec 13;12:780924. doi: 10.3389/fphar.2021.780924

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Copyright © 2021 Ji, Li, Mo, Lu, Lu, Lin, Liu, Zou and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Serum TMAO and its precursors. Serum TMAO and TMA in 5/6 nephrectomy rats were markedly increased, but reduced significantly by rhubarb enema. TMAO, trimethylamine-N-oxide. TMA, trimethylamine.