TABLE 3.

General conditions and biochemical analysis.

Parameters	Sham (n = 8)	5/6Nx (n = 8)	5/6Nx + rhubarb L (n = 8)	5/6Nx + rhubarb H (n = 8)
Body weight (g)	543.88 ± 86.82	540.13 ± 60.09	530.75 ± 28.62	534.25 ± 59.83
Residual kidney weight (mg)	1361.38 ± 140.81	1858.13 ± 355.82*	1977.63 ± 264.75	1805.13 ± 235.24
Residual kidney weight/Body weight (mg/g)	2.50 ± 0.13	3.47 ± 0.75	3.73 ± 0.47	3.38 ± 0.19
Serum Creatinine (baseline, μmol/L)	24.40 ± 3.51	72.75 ± 13.94*	68.38 ± 9.75	72.50 ± 17.08
Serum Creatinine (The end, μmol/L)	67.30 ± 10.18	120.27 ± 13.79*	101.81 ± 12.21#	97.95 ± 11.93#
Urea (mmol/L)	4.57 ± 0.39	8.84 ± 1.84*	8.12 ± 0.90	5.33 ± 0.83#
Urine volume (ml)	13.50 ± 2.45	29.63 ± 5.26*	23.75 ± 4.71#	27.50 ± 7.89
Urine Creatinine (μmol/L)	12,569.50 ± 4,240.85	6,425.63 ± 2917.77*	9,228.75 ± 513.27#	6,688.63 ± 1710.85
Urine protein concentration (mg/L)	811.00 ± 466.83	993.88 ± 820.56	1282.25 ± 343.22	921.25 ± 805.56
UPCR (g/g)	0.54 ± 0.13	0.84 ± 0.22*	1.23 ± 0.34	1.23 ± 1.18

Abbreviations: UPCR, urine protein creatinine ratio. 5/6Nx, 5/6 nephrectomy. 5/6Nx + rhubarb L, 5/6 nephrectomy + low dose rhubarb enema. 5/6Nx + rhubarb H, 5/6 nephrectomy + high dose rhubarb enema. * vs sham, # vs model.