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. 2021 Dec 13;12:737586. doi: 10.3389/fendo.2021.737586

Table 1.

General characteristics of the study population according to gender.

Variables Total (n = 400)
mean ± SD
Men (n = 141)
median (IQR)
Women (n = 259)
median (IQR)
p value
Age (year) 64.47 ± 8.45 64 [60, 72] 62 [57, 70] 0.005
BMI (kg/m2) 24.55 ± 3.57 24.6 [22.2, 27.2] 23.9 [22.4, 26.7] 0.32
Waist circumference (cm) 85.07 ± 9.68 89 [84, 95] 81 [77, 88] <0.001
VAI 1.84 ± 1.38 1.4 [0.8, 2.1] 1.5 [1.0, 2.3] 0.046
BUN (mg/dL) 15.92 ± 5.99 15.7 [13.4, 9.4] 14.3 [11.8, 17.5] 0.003
Creatinine (mg/dL) 0.78 ± 0.43 0.9 [0.8, 1.0] 0.6 [0.6, 0.7] <0.001
eGFR (ml/min/1.73m2) 112.97 ± 33.43 93.6 [83.0, 117.2] 123.9 [101.7, 137.3] <0.001
Glucose(AC) (mg/dL) 96.23 ± 25.73 92 [86, 102] 90 [82, 100] 0.06
HDL-C (mg/dL) 54.43 ± 13.93 46 [39, 53] 57 [48, 66] <0.001
LDL-C (mg/dL) 118.37 ± 32.11 109 [86, 132] 119 [101, 141] 0.002
T-Cholesteterol (mg/dL) 197.15 ± 35.71 183 [158, 209] 202 [179, 226] <0.001
Triglyceride (mg/dL) 122.07 ± 65.97 110 [76, 151] 106 [79, 144] 0.82
SBP (mmHg) 129.50 ± 16.71 129 [119, 140] 128 [117, 139] 0.40
DBP (mmHg) 76.93 ± 11.36 80 [72, 86] 76 [69, 82] 0.002
Current smoking, n(%) 43 10.75% 35 24.8% 8 3.1% <0.001
Alcohol drinking ≧2 times/week, n(%) 75 18.75% 47 33.3% 28 10.8% <0.001
ACR ≧30 mg/g, n(%) 75 18.75% 29 20.6% 46 17.8% 0.49
HTN, n(%) 201 50.25% 77 54.6% 124 47.9% 0.20
DM, n(%) 79 19.75% 30 21.3% 49 18.9% 0.57
Hyperlipidemia, n(%) 260 65.00% 84 59.6% 176 68.0% 0.09
CKD, n(%) 81 20.25% 31 22.0% 50 19.3% 0.52
Chinese herb use, n(%) 129 32.25% 50 35.5% 79 30.5% 0.31
Analgesics use, n(%) 32 8.00% 11 7.8% 21 8.1% 0.91

Clinical characteristics are presented as mean ± standard deviation (SD) and median with inter-quartile range (IQR) for continuous variables and n (%) for categorical variables. P-value were derived from Mann-Whitney U test for continuous variables and chi-square test for categorical variables.

BMI, body mass index; VAI, visceral adiposity index; BUN, blood urea nitrogen; eGFR, estimated glomerular filtration rate; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; T-cholesterol, total cholesterol; SBP, systolic blood pressure; DBP, diastolic blood pressure; ACR, urine albumin creatinine ratio; HTN, hypertension; DM, diabetes mellitus; CKD, chronic kidney disease.