Table 2.
Factors associated with no receipt of HCC treatment
| Characteristic | Univariate | Multivariable | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P Value | OR | 95% CI | P Value | |
| Age (10‐year change) | 1.17 | 1.16, 1.19 | <0.001 | 1.19 | 1.17, 1.22 | <0.001 |
| Sex | ||||||
| Male | — | — | — | — | ||
| Female | 0.99 | 0.96, 1.02 | 0.669 | 1.03 | 0.99,1.07 | 0.134 |
| Race | ||||||
| White | — | — | — | — | ||
| Hispanic | 1.30 | 1.26, 1.35 | <0.001 | 1.18 | 1.13, 1.23 | <0.001 |
| Black | 1.22 | 1.17, 1.26 | <0.001 | 1.16 | 1.11, 1.21 | <0.001 |
| Asian + others | 0.91 | 0.86, 0.96 | <0.001 | 0.94 | 0.89, 0.99 | 0.023 |
| Insurance status | ||||||
| Not insured | — | — | — | — | ||
| Private | 0.31 | 0.29, 0.33 | <0.001 | 0.37 | 0.35, 0.40 | <0.001 |
| Medicaid/Medicare | 0.48 | 0.45, 0.51 | <0.001 | 0.49 | 0.46, 0.52 | <0.001 |
| Other | 0.34 | 0.30, 0.38 | <0.001 | 0.40 | 0.35, 0.44 | <0.001 |
| High school | ||||||
| 82.4% or less | — | — | — | — | ||
| 82.5%‐89.1% | 0.86 | 0.83, 0.89 | <0.001 | 0.90 | 0.86, 0.93 | <0.001 |
| 89.2%‐93.7% | 0.76 | 0.74, 0.79 | <0.001 | 0.86 | 0.82, 0.91 | <0.001 |
| More than 93.7% | 0.63 | 0.60, 0.65 | <0.001 | 0.76 | 0.71, 0.80 | <0.001 |
| Median Income | ||||||
| Less than $40,227 | — | — | — | — | ||
| $40,227‐$50,353 | 0.89 | 0.86, 0.93 | <0.001 | 0.94 | 0.91, 0.99 | 0.007 |
| $50,354‐$63,332 | 0.81 | 0.77, 0.84 | <0.001 | 0.89 | 0.86, 0.94 | <0.001 |
| $63,333+ | 0.69 | 0.67, 0.72 | <0.001 | 0.87 | 0.83, 0.93 | <0.001 |
| Community type | ||||||
| Metro | — | — | — | — | ||
| Urban | 1.01 | 0.97, 1.05 | 0.643 | 0.91 | 0.87, 0.96 | <0.001 |
| Rural | 1.16 | 1.03, 1.30 | 0.010 | 0.96 | 0.83, 1.07 | 0.560 |
| Year of diagnosis | 0.96 | 0.96, 0.97 | <0.001 | 0.96 | 0.95, 0.96 | <0.001 |
| Facility type | ||||||
| Academic | — | — | — | — | ||
| Community cancer program | 5.13 | 4.84, 5.43 | <0.001 | 3.85 | 3.51, 3.96 | <0.001 |
| Comprehensive community cancer program | 2.84 | 2.75, 2.93 | <0.001 | 2.42 | 2.31, 2.48 | <0.001 |
| Integrated network | 1.76 | 1.68, 1.83 | <0.001 | 1.60 | 1.52, 1.66 | <0.001 |
| Region | ||||||
| Northeast | — | — | — | — | ||
| Midwest | 0.93 | 0.89, 0.97 | <0.001 | 0.82 | 0.79, 0.86 | <0.001 |
| South | 1.22 | 1.18, 1.27 | <0.001 | 0.93 | 0.89, 0.97 | <0.001 |
| West | 1.20 | 1.15, 1.26 | <0.001 | 1.02 | 0.97, 1.07 | 0.515 |
| Charlson comorbidity | ||||||
| 0 | — | — | — | — | ||
| 1 | 0.90 | 0.87, 0.93 | <0.001 | 0.91 | 0.88, 0.95 | <0.001 |
| 2 | 0.87 | 0.83, 0.91 | <0.001 | 0.93 | 0.89, 0.99 | 0.007 |
| ≥3 | 1.22 | 1.18, 1.26 | <0.001 | 1.33 | 1.29, 1.39 | <0.001 |
| TNM stage | ||||||
| Stage 1 | — | — | — | — | ||
| Stage 2 | 0.95 | 0.91, 1.00 | 0.048 | 0.97 | 0.93, 1.02 | 0.201 |
| Stage 3 | 2.37 | 2.28, 2.47 | <0.001 | 1.80 | 1.78, 1.92 | <0.001 |
| Stage 4 | 3.91 | 3.76, 4.07 | <0.001 | 2.59 | 2.57, 2.79 | <0.001 |
| AFP | ||||||
| Negative | — | — | — | — | ||
| Positive | 1.73 | 1.67, 1.79 | <0.001 | 1.22 | 1.16, 1.24 | <0.001 |
| MELD (10‐unit change) | 1.78 | 1.74, 1.81 | <0.001 | 1.33 | 1.31, 1.35 | <0.001 |
| Tumor size (1‐cm change) | 1.16 | 1.14, 1.18 | <0.001 | 1.00 | 1.00, 1.01 | <0.001 |
Abbreviation: OR, odds ratio.