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. 2021 Sep 10;48:102129. doi: 10.1016/j.redox.2021.102129

Fig. 1.

Fig. 1

(A) Chemical structures and Keap1–Nrf2 binding inhibition IC50 values of the cyclometalated iridium (III) and rhodium (III) complexes 16, 1a1e, 1023, the ligands 7 and 8, and positive control 9 (ML334) evaluated in this study using a FP assay. (B) Summary of SAR for these complexes.