Extended Data Figure 2.

a, Examples of spontaneous excitatory postsynaptic potentials (sEPSCs) recorded from neurons of the superficial laminae of the spinal dorsal horn of nerve-injured rats. b, sEPSC frequency and amplitude were reduced following superfusion of VCP171 or MIPS521, which is reversed by the antagonist, DPCPX (n=8 per group); Data are presented as mean values +/− SEM. Significance compared to baseline was determined using a two-tailed paired t test, * P < 0.05, ** P < 0.01.