TABLE 2.

Exsomes ncRNAs AND drug resistance.

NcRNA	Host cells	Mechanism of function	References
miR-522	Cancer-associated fibroblasts (CAFs)	ferroptosis↓;lipid-ROS accumulation↓	Zhang et al. (2020d)
miR-21	tumor-associated macrophages (TAMs)	exosomal transfer;PTEN↓	Zheng et al. (2017)
miR-500a-3p	cisplatin-resistant GC cells	stemness properties↑	Lin et al. (2020)
miR-155-5p	paclitaxel-resistant GC cells	EMT↑;chemoresistant phenotypes↑	Wang et al. (2019)
miR-106a-5p and miR-421	5-fluorouracil-resistant GC cells	TFAP2E methylation↑	Jingyue et al. (2019)
miR-501	doxorubicin-resistant GC cells	BH3-like motif-containing protein(BLID)↑	Liu et al. (2019b)
miR-214	HEK293T	potential targets↑;apoptosis↑	Wang et al. (2018c)
circPRRX1	doxorubicin-resistant GC cells	miR-3064-5p↓;PTPN14↑	Wang et al. (2020b)