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. 2021 Dec 13;9:802745. doi: 10.3389/fcell.2021.802745

TABLE 3.

NcRNAs in HER2-positive GC.

ncRNA Main contents Mechanism of function References
miR-494 lapatinib fibroblast growth factor receptor 2(FGFR2)↓;cancer initiating cells (CICs)↓ Yu et al. (2018)
miR-143 growth KRAS network↓;DDX6 RNA helicase↓ Tokumaru et al. (2019)
miR-21 trastuzumab PTEN↓;AKT phosphorylation↑ Eto et al. (2014)
miR-223 terrazumab F-box and WD repeat domain-containing 7 (FBXW7)↓ Eto et al. (2015)