Table 3.
Test performance characteristics and estimated prevalence of WANTAI and KWTRP ELISAs for SARS-CoV-2 antibodies in different test populations.
| Test population | WANTAI | KWTRP | |||
|---|---|---|---|---|---|
| N | Negative | Specificity | Negative | Specificity | |
| Pre-pandemic samples (gold standard negative) | |||||
| Adults, coastal Kenya blood donors, 2018 | 327 | 320 | 0.979 | 326 | 0.997 |
| Adults, cross-sectional survey, 2018 | 189 | 187 | 0.989 | 189 | 1.000 |
| N | Positive | Sensitivity | Positive | Sensitivity | |
| Pandemic positives (gold standard positive) | |||||
| SARS-CoV-2 PCR positive cohort | 149 | 142 | 0.953 | 138 | 0.926 |
| N | Positive | Prevalence | Positive | Prevalence | |
| Test samples (unknowns) | |||||
| COVID-19 diagnostic testing patients | 676 | 121 | 0.179 | 103 | 0.152 |
| Adults, Kenya blood donors COVID-19 wave 1 | 176 | 4 | 0.023 | 2 | 0.011 |
| Adults, Kenya blood donors COVID-19 wave 4 | 176 | 146 | 0.830 | 136 | 0.773 |