Fig. 6.

Effects of MCTR1 on ALI, intestinal mucosal damage, and survival in CLP-induced sepsis. A Mice were given MCTR1 (200 ng/mice, iv) 0.5 h before being subjected to CLP, and then an additional MCTR1 (200 ng/mice, iv) was given 12 h after CLP. All samples were collected 24 h after CLP. Representative HE stains images of lung and intestinal sections (n = 6 mice/group). B Histological analyses of CLP-induced ALI and AII. C Mice were given MCTR1 (200 ng/mice, iv) 0.5 h before being subjected to CLP, and then an additional MCTR1 (200 ng/mice, iv) was given 12 h after CLP. The survival rate (n = 10 mice/group) was recorded for 7 consecutive days. Mean ± SD were presented. **P < 0.01