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. Author manuscript; available in PMC: 2022 Apr 30.
Published in final edited form as: Biochem Soc Trans. 2021 Apr 30;49(2):645–661. doi: 10.1042/BST20200394

Table 1.

Structures of the MET ECD

PDB ID Technique MET domains Other ligands/proteins
Sema PSI IPT1 IPT2 IPT3 IPT4
1SHY X-ray + + HGF β-chain
2UZX X-ray + + + InlB
2UZY X-ray + + + +
4O3T X-ray + + HGF β-chain + Zymogen Activator Peptide (ZAP.14)
4O3U X-ray + + HGF β-chain + Zymogen Activator Peptide (ZAP2.3)
6GCU X-ray + + + + InlB and DARPin A3A
6I04 X-ray + + Fab
4K3J X-ray + + HGF β-chain + Fab (Onartuzumab)
1SSL NMR + -
5LSP X-ray + + + Fab (107_A07)