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. Author manuscript; available in PMC: 2022 Oct 13.
Published in final edited form as: J Am Chem Soc. 2021 Oct 1;143(40):16580–16588. doi: 10.1021/jacs.1c06572

Figure 3.

Figure 3.

Synthetic applications of rAP. (A) Reductive removal of Evans auxiliary with high chemoselectivity among multiple carbonyl groups. (B) Highly chemoselective reduction for diversification of PROTAC molecules. (C) Rapid deoxygenation of thalidomide analogs and modulation of cereblon binding affinity.