Figure 5. EPZ005687 induces ERVs, LINE-1, and an interferon response in transformed cells.
A673, RD, RMS13, SK-N-BE(2), Y79, WERI-Rb-1, 293T, HCT116, IMR-90, human umbilical vein endothelial cells (HUVEC), and ARPE-19 cells were treated with the indicated concentration of EPZ005687 for 72 hours and the expression of the indicated genes was analyzed by qRT-PCR. *p < 0.05 compared with untreated cells.