Table 3.
Scoring for survival.
| Risk factors for overall survival | |||
|---|---|---|---|
| Residual tumor volume (cm3) | ≤10 | >10 to ≤ 20 cm3 | >20 |
| 10 | 4 | 0 | |
| Age (years) | ≤50 | >50 to ≤ 70 | >70 |
| 6 | 2 | 0 | |
| MGMT | Methylated | Unmethylated | |
| 5 | 0 | ||
| Therapy modality | Radiochemotherapy | Radiotherapy | Chemotherapy |
| 6 | 2 | 0 | |
| Resectability | Good | Bad | |
| 3 | 0 | ||
| Infiltration of ventricular wall | No | Yes | |
| 4 | 0 | ||
The “worst” score (with the worst forecast) is thus 0; the best value is 34. The AFT model (χ2 = 166.95; p < 0.0001, see document, Supplementary File 1 , Scoring for survival “2,” p. 15) of the score demonstrated a pseudo R2 of 0.423 and a C-index of 0.748 and was validated on the independent data set with a pseudo R2 of 0.239 and a C-index of 0.678 resulting in a median APE of 2.78 months (mean: 1.83 months).
MGMT, O6-methylguanine-DNA-methyltransferase.