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. 2021 Dec 13;12:794458. doi: 10.3389/fphar.2021.794458

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Copyright © 2021 Shi, Li, Zhang, Chen, Gao, Zhang, Shang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Baicalein decreased the expression of PDE2A, PDE4A, PDE4B, and PDE4D in the hippocampus of Aβ-treated mice. All values are expressed as mean ± SEM (n = 6). ***p < 0.001 vs. NC mice; #p < 0.05, ##p < 0.01, ##p < 0.001 vs. Aβ-treated mice.