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Baicalein increased cAMP- and cGMP-downstream proteins expression in the hippocampus of Aβ-treated mice. (A,B) The levels of cAMP/cGMP and (C–E) PKA and PKG, (F,G) the ratio of pCREB/CREB, and (H) the expression of BDNF were increased by baicalein treatment in Aβ-treated mice. All values were expressed as mean ± SEM (n = 6). ** p < 0.01, *** p < 0.001 vs. NC mice; # p < 0.05, ## p < 0.01, ### p < 0.001 vs. Aβ-treated mice.
