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. 2021 Dec 28;146:112481. doi: 10.1016/j.biopha.2021.112481

Table 3.

Multivariate model of mortality.

Adjusted HR 95% CI p
ATB 1.539 [0.706; 3.354] 0.278
MDRD at admission 0.994 [0.986; 1.002] 0.163
Leucocyte count at admission 1.097 [1.022; 1.178] 0.010
Saturation at admission 0.927 [0.891; 0.964] 0.0001

Adjustment for the variables linked to the primary endpoint at the 5% threshold in univariate analysis (previous table).

Note: there was no adjustment for CRP or O2 because these variables are linked to antibiotic use and increase the variance of the estimators by more than 20% (VIF test).