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. Author manuscript; available in PMC: 2021 Dec 31.
Published in final edited form as: IEEE Trans Biomed Circuits Syst. 2020 Dec 31;14(6):1241–1252. doi: 10.1109/TBCAS.2020.3037862

Table III.

Comparison table with State-of-the-Art mm-Scale Wireless Neurostimulators

This Work Neuron′17 [11] ISSCC′18 [13] TBioCAS′18 [14] TBioCAS′19 [15] Nat. Biomed. Eng.′20 [21]
Application Target Spinal Cord Brain Brain PNS Brain PNS
Process (nm) 180 Discrete 350 180 130 65
Wireless Link Magnetoelectric Inductive Inductive Inductive Inductive Ultrasonic
Carrier Freq. (MHz) 0.25 13.56 60 198 1180 1.85
Implant Volume (mm3) 8.2 98 12.2 97.5 0.009 1.7
Stimulation Mode Biphasic
Current
Optical Optical Monophasic Voltage Monophasic Voltage Monophasic Current
Max. Stim. Current (mA) / Resolution (bit) 1.5 / 5 N/A N/A 0.25 / Fixed 0.04 / Fixed 0.4 / 3
Max. Stimulation Charge (nC) 391 N/A N/A 17.5 0.66 157
Stimulating Channels 1 1 16 1 1 1
SoC Power (μW) 23.7 N/A 300 2.7 N/A 4
Max. Overall Efficiency (%) @ Distance (mm) 0.435 @ 0
0.064 @ 30
N/A N/A N/A 0.0019 @ 6.6 0.06 @ 18
Max. Operating Depth (mm) 30 40 7 140 6.6 55
In-Vivo Test Model Hydra Rat Rat Rat Rat Rat