Table 4.

2-TCM parameters for (S)-[¹⁸F]GE387 obtained from the striata in the control animals and from contralateral and ipsilateral striata in the LPS neuroinflammation model (mean ± SEM). Differences between groups were examined using 2-way ANOVA followed by Bonferroni post hoc analysis for each of the parameters

2-TCM parameters	(S)-[18F]GE387 control (n = 9)	(S)-[18F]GE387 contralateral (n = 3)	P	(S)-[18F]GE387 ipsilateral (n = 3)	P
K1	0.19 ± 0.02	0.25 ± 0.09	ns	0.52 ± 0.19	ns
k2	0.24 ± 0.04	0.30 ± 0.11	ns	0.71 ± 0.33	ns
k3	0.07 ± 0.03	0.12 ± 0.05	ns	0.35 ± 0.14	ns
k4	0.03 ± 0.01	0.06 ± 0.02	ns	0.07 ± 0.01	ns
VT	2.40 ± 0.22	2.35 ± 0.41	ns	5.28 ± 0.92	< 0.001
K1/k2	0.89 ± 0.09	0.95 ± 0.16	ns	1.12 ± 0.41	ns
BPND = k3/k4	1.86 ± 0.28	1.60 ± 0.49	ns	5.10 ± 1.91	< 0.001