Table 1.
Clinical value of the autophagy-related lncRNA prognostic signature for HCC.
| Characteristics | Group | Risk score | ||
|---|---|---|---|---|
| N | Mean | P value | ||
| Age (years) | <60 | 157 | 1.154 | 0.787 |
| ≥60 | 186 | 1.183 | ||
| Gender | Male | 233 | 1.114 | 0.120 |
| Female | 110 | 1.289 | ||
| Alcohol consumption | Present | 109 | 1.106 | 0.482 |
| Absent | 218 | 1.185 | ||
| Liver cirrhosis | Present | 131 | 1.254 | 0.353 |
| Absent | 65 | 1.112 | ||
| Family history | Present | 104 | 1.063 | 0.165 |
| Absent | 194 | 1.216 | ||
| Histological grade | G1+G2 | 211 | 1.159 | 0.699 |
| G3+G4 | 138 | 1.202 | ||
| Albumin (g/dl) | <4.0 | 128 | 1.055 | 0.633 |
| ≥4.0 | 153 | 1.105 | ||
| Creatinine (mg/dl) | <1.1 | 189 | 0.926 | 0.005 |
| ≥1.1 | 92 | 1.169 | ||
| BMI (kg/cm2) | <25 | 143 | 1.163 | 0.776 |
| ≥25 | 152 | 1.196 | ||
| AFP (ng/ml) | ≤ 200 | 187 | 0.977 | 0.006 |
| >200 | 73 | 1.408 | ||
| ECOG | =0 | 156 | 1.094 | 0.196 |
| >0 | 117 | 1.253 | ||
| T stage | I+II | 252 | 1.042 | 0.002 |
| III+IV | 88 | 1.551 | ||
| TNM stage | I+II | 238 | 1.025 | 0.001 |
| III+IV | 83 | 1.576 | ||
Bold font represents P < 0.05 and the relevant variables are statistically significant.
HCC, hepatocellular carcinoma; HBV, hepatitis B virus; HCV, hepatitis C virus; AFP, alpha-fetoprotein; BMI, body mass index; ECOG, eastern cooperative oncology group; TNM, tumor node metastasis; SD, standard deviation.