Figure 1.

Occupancy of D₂ and D₃ receptors of antipsychotics. The cariprazine and aripiprazole data come from a PET study involving healthy volunteers that aimed to assess the D3 receptor occupancy of cariprazine and aripiprazole at doses that attain similar D2 receptor occupancy by both drugs. This was assessed using two different methods, and the data presented here is the average of the outcome of these methods. The brexpiprazole data comes from a PET study involving schizophrenia patients.