Table 3.
The changes of CD4+ or CD8+ T cells between VD and CD group in different age.
| Age (years) | CD4+ and/or CD8+ T cells | VD | CD | P | ||
|---|---|---|---|---|---|---|
| N | Values | N | Values | |||
| <=1 | CD3+CD4+ | 285 | 2709.55 ± 1448.23 | 285 | 2730.23 ± 1229.15 | 0.85 |
| CD3+CD4+% | 285 | 39.44 ± 9.99 | 285 | 42.32 ± 10.4 | <0.01 | |
| CD3+CD8+ | 285 | 1411.55 ± 1120.13 | 285 | 1311.94 ± 1795.2 | 0.43 | |
| CD3+CD8+% | 285 | 19.88 ± 7.64 | 285 | 18.31 ± 7.48 | 0.01 | |
| CD4/CD8 | 285 | 2.35 ± 1.24 | 285 | 2.78 ± 1.71 | <0.01 | |
| 1~2 | CD3+CD4+ | 149 | 2029.22 ± 1230.33 | 132 | 1777.88 ± 1159.99 | 0.08 |
| CD3+CD4+% | 149 | 35.29 ± 10.04 | 132 | 32.98 ± 9.93 | 0.05 | |
| CD3+CD8+ | 149 | 1230.47 ± 1028.16 | 132 | 1423.72 ± 1818.7 | 0.28 | |
| CD3+CD8+% | 149 | 20.85 ± 8.45 | 132 | 21.91 ± 10.44 | 0.35 | |
| CD4/CD8 | 149 | 1.99 ± 1.05 | 132 | 1.85 ± 1 | 0.25 | |
| 2~3 | CD3+CD4+ | 111 | 1546.62 ± 795.08 | 86 | 1620.31 ± 1019.01 | 0.58 |
| CD3+CD4+% | 111 | 33.38 ± 10.47 | 86 | 32.57 ± 9.61 | 0.58 | |
| CD3+CD8+ | 111 | 1618.94 ± 3026.34 | 86 | 1512.16 ± 2110.83 | 0.77 | |
| CD3+CD8+% | 111 | 24.65 ± 13.66 | 86 | 23.96 ± 13.6 | 0.73 | |
| CD4/CD8 | 111 | 1.73 ± 0.95 | 86 | 1.7 ± 0.86 | 0.82 | |
| 3~4 | CD3+CD4+ | 114 | 1308.25 ± 657.97 | 106 | 1140.97 ± 676.21 | 0.06 |
| CD3+CD4+% | 114 | 33.33 ± 9.99 | 106 | 32.23 ± 8.65 | 0.39 | |
| CD3+CD8+ | 114 | 1640.97 ± 3843.35 | 106 | 1098.22 ± 1865.17 | 0.18 | |
| CD3+CD8+% | 114 | 26.19 ± 13.69 | 106 | 23.55 ± 12.04 | 0.13 | |
| CD4/CD8 | 114 | 1.56 ± 0.71 | 106 | 1.64 ± 0.73 | 0.39 | |
| 4~5 | CD3+CD4+ | 94 | 1098.02 ± 610.15 | 54 | 1183.16 ± 676.25 | 0.45 |
| CD3+CD4+% | 94 | 33.13 ± 9.58 | 54 | 32.77 ± 7.47 | 0.8 | |
| CD3+CD8+ | 94 | 1144.09 ± 1900.14 | 54 | 1191.64 ± 1865.78 | 0.88 | |
| CD3+CD8+% | 94 | 25.35 ± 12.12 | 54 | 25.8 ± 10.53 | 0.82 | |
| CD4/CD8 | 94 | 1.56 ± 0.92 | 54 | 1.45 ± 0.57 | 0.37 | |
| 5~6 | CD3+CD4+ | 32 | 1044.18 ± 575.18 | 30 | 1051.5 ± 777.02 | 0.97 |
| CD3+CD4+% | 32 | 30.47 ± 9.66 | 30 | 32.88 ± 10.35 | 0.35 | |
| CD3+CD8+ | 32 | 1544.19 ± 2633.29 | 30 | 1046.16 ± 1942.18 | 0.4 | |
| CD3+CD8+% | 32 | 30.27 ± 14.39 | 30 | 24.22 ± 12.2 | 0.08 | |
| CD4/CD8 | 32 | 1.18 ± 0.51 | 30 | 1.57 ± 0.67 | 0.01 | |
CD, caesarean delivery; VD, vaginal delivery; N, Number of sample size; CD3+, The number of CD3+ T cells/μl; CD3+%, The ratio of CD3+ T cell in total lymphocyte; CD3+CD4+, The number of CD3+CD4+ T cells/μl; CD3+CD4+%, The ratio of CD3+CD4+ T cell in total lymphocyte; CD3+CD8+, The number of CD3+CD8+ T cells/μl; CD3+CD8+%, The ratio of CD3+CD8+ T cell in total lymphocyte; CD4/CD8, the ratio of CD4+ T cell versus CD8+ T cell; CD3+/HLA-DR+, The number of CD3+/HLA-DR+ T cells/μl; CD3+/HLA-DR+%, The ratio of CD3+/HLA-DR+ T cell in total lymphocyte; Treg, The number of regulatory T cells/μl; Treg%, The ratio of regulatory T cell in total lymphocyte; CD3-/CD19+, The number of B cells/μl; CD3-/CD19+%, The ratio of B cell in total lymphocyte; CD45+, The number of CD45+ cells/μl; NK, The number of NK cells/μl; NK%, The ratio of NK cell in total lymphocyte; CD14+/HLA-DR+, The number of activated monocytes cells/μl; CD14+/HLA-DR+%, The ratio of activated monocytes in total monocytes.
All tests of these cells are done by flow cytometry. The absolute number (cells/µL) of positive cells in the sample can be determined by comparing cellular events to bead events. Absolute counts of cells are calculated by BD FACSCanto clinical software using the following formula: cell population absolute count test volume = (events in cell population/events in absolute count bead region)*(beads of each test/ test volume).
The bold values meant the significant difference between two groups.