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. 2021 Dec 27;11:24448. doi: 10.1038/s41598-021-03931-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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SARS-CoV-2 IgG antibody time course trajectories of participants receiving either Pfizer or Moderna vaccines were largely similar. (A) Relative quantification of SARS-CoV-2 IgG antibodies in participants who received the Moderna vaccine (N = 51) reveal increasing concentration in the days following the first and second dose. The average antibody concentration of participants prior to receiving vaccination was 0.66 ± 0.09 ng/mL while 90 days after vaccination this number stabilized at 151.7 ± 118.5 ng/mL. (B) Similarly, antibody concentration increased following vaccination by the Pfizer vaccine (N = 79). The average antibody concentration of participants prior to receiving vaccination was 0.35 ± 0.14 ng/mL while 90 days after vaccination this number stabilized at 70.32 ± 35.42 ng/mL. (C) Time courses of antibody development are well-aligned across the two vaccines.