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. 2021 Oct 12;7(4):368–398. doi: 10.3934/microbiol.2021023

Table 4. mRNA-based vaccines using Lipid nanoparticles (LNPs) for the delivery of cargo.

Vaccine Developer Trial phase
ARCoV Walvax Biotechnology Co., Ltd.; Abogen Biosciences Co. Ltd.; Yuxi Walvax Biotechnology Co., Ltd. Phase 3
CVnCoV CureVac; GSK Phase 2b/3
DS-5670a Daiichi Sankyo Co., Ltd. Phase 1/2
MRT5500 Sanofi, Translate Bio Phase 1/2
LUNAR-COV19 (ARCT-021) Arcturus/Duke-NUS/Catalent Phase 1/2
LNP-nCoVsaRNA Imperial College Phase 1/2
(Not named yet) Shanghai Municipal Science and Technology Commission; Stemirna Therapeutics Phase 1
(Not named yet) Gritstone Oncology, Inc.; National Institute of Allergic and Infectious diseases (NIAID) Phase 1
PTX-COVID19-B Providence Therapeutics; Canadian government Phase 1
ChulaCov19 Chulalongkorn University Phase 1
D614G variant LNP Encapsulated RNA (Bancovid, Banagavax) Globe Biotech Ltd Pre-clinical
LNP-encapsulated mRNA encoding S Max-Planck-Institute of Colloids and Interfaces Pre-clinical
Comirnaty (BNT162b2) Pfizer, BioNTech; Fosun Pharma Authorized or approved
Moderna COVID-19 Vaccine (mRNA-1273) Moderna, Biomedical Advanced Research and Development Authority (BARDA), National Institute of Allergic and Infectious diseases (NIAID) Authorized or approved

Source: World Health Organization [116].